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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589479cb099d5dc2c72cde456ec3ddcc4088e6b364ed01200d310c5d1b3bcbbf' 
  AND token = 'qxopNKosL5NjDMgk87Ca0gXARtt3abQCB5oOsjauYkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}