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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead03ba2735d7b3d31a0c46088d4baef88397fa2eaf9d10b260301a08de39fc0' 
  AND token = 'xP8cIT5mPBjlc2dLuU+sQzryHrhXj+xB7O1FzsLGrdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}