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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b46d0ce762116a234455303da86f960cd4a893b172b390b6c64a2ad7c7abcd' 
  AND token = '7c1qMb+zE49RESgSmH/vocb393c5IMVyuUyq/CtgdZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}