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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790abb7c4d28e93b5fe2120a897a1218b456a8b7234e80d0d302142e9e8c8c7c' 
  AND token = 'Kv4nkLALtpTp5qs0FBN0nD9lokuexkTCIKPq8dZR9fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}