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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd77e52fd9c2045ad1173923a3826dae848f5566dfb04546a68518427621e3c' 
  AND token = 'oPUar0aAZGVX7cDGgRE/oIlskR2vBPM40ige210Xsxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}