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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b5f18ca60fe112063a0f90904fad139b0b5345328bc7b52428122958bad850' 
  AND token = 'aUDdGQX+RNQqwp0aEYKGDz4EX3bXpFmLNCWk1lc6t3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}