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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43cee82a51e0e5d49c970e46424c5d5426ba094faf11aca76c9cd1ae12d6c949' 
  AND token = 'tQr5AR//TJ6s++W1E41b0JFlo0RkJu5+SVSfypcLXGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}