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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46fb256ebc7c65455f5142b87a024b2788640ebf638bf79bcb1677f87a4ab1d9' 
  AND token = '17SkdfRowwwZ+QhgQ6fGXwmwJlh9D4j98wwQLAPXfcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}