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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6b2c04581308061e65d0914f572d4c40073f0c87b4c8d13b4b3994d8da4bc9' 
  AND token = 'kO1T+IkngRPcrl6NhqMHpr69fILYbfYt9L1kRJj0xcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}