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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af32ed134b4543fbc733790803f1e92d24e80d6a4f461b441687f095734b3241' 
  AND token = 'i1U492R2+biqgk6Fa3ZwmbGCYXWzB/dqbPXeVC9UtWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}