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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf773371f1e56cb500791e52d15737cbcc325944682e60d634718fb6bb1395f' 
  AND token = 'vcFr9k45bfukdGxpcAczFe6diQbo+x7AnP40l4B7Wus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}