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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e1a1d5e850bdb8442879e75253d22e5b8a58fbd7dbebf431e6b88e29dd7004' 
  AND token = 'V2GUdHj6h/VjW4pAm5io16iYEJAAVwtYHpjgr0BymVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}