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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c774702c3a8c9e3fc9c51a8fcbfc6773619959633e206b1c5dd998da3aa68e' 
  AND token = 'WRO0g9GtM9sUropmdVW6ev7yduJioct/sabTSLrNKMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}