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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db5644620d27256ff694a38a9ce46b6b6cbe253575498b07bd79d50da72b0511' 
  AND token = 'AKOQP9yKJ7KZ2I+TvH1p0HN6Y7mnlmM/aNdV2gJcF9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}