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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781a85e93cabac2d5c770385f6ab260af90f96dcbf7fa2f8acfd28e357bfb715' 
  AND token = 'c0D4bsiROOzXLjmqV8vaIzr4CtNk3sG9gnEsaPGgtyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}