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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c03e061fa4fe77881a9da4166758620537a1c9deb1781be05dc6b0aa7a557bd' 
  AND token = 'wjZzTViHDycWyPZSI8EIJCLZEsXhl1onyzWXWtyD1Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}