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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686162b51d37b1484ff106d00cd268491a31b0ccb5340caf6a8527289867eb6e' 
  AND token = 'EdOUma9p9TytTNoFArdLbLkv8LJR5S57aHbEQ+RtkBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}