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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7787cc30b3631bb8d7c56f9b09180a738a1131435d5da2d948792430853f347c' 
  AND token = 'SbaQDKXKw8z5Co3/NEaEE+9CfD52CbDIcveVw14OKVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}