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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f861bfda9647e9ec6d91e25fee26b5da3eb80e200f2f30d8f6c6ced257f54e0' 
  AND token = '0DEqERZ2T49ZP36VKrOAhTZoEik/GBV2xzDW9vtSqL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}