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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eecbe51ac755339ee9801ef90ad314ed41b80d0b933fa3f90f53271ad6dd29e' 
  AND token = 'PNtmBUVXmShVrUQ/rhKfQheG4Q0MBQkQpwFX1Y7B4yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}