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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8080a5f8d18f9ec3d64e53c855d0aba255288f2fd2ad7e4b62e57c4d022e6d' 
  AND token = 'l3LE/sQtBg1IYPtQR+mY3nJUO84wC0QMXUYOLz5o8EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}