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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76f94764a30c95af806cc74d3c820a6bfeaa15e486b0133fb18e3f1905add30d' 
  AND token = '+PgFA46v6x6QMdIAIDNzOb21cXrJJmaNtYgw2vR9ZoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}