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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49c6f3a8513db87c52c8900b9c13f527d1ac20dd8569496928bc9840ea1976a' 
  AND token = '0NFW4TzZR5IenWrVbwCDs/97XapF0j1uXH7ST+lVycA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}