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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d43123379809dfba796cad495473e0e14838d184ab2337e3507b1f85186c373' 
  AND token = '10w+Sgaiz36Tp8unVF1exqFFxBUx0G6/6GIdJggu0GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}