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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e9772e76bcdc17eb756923f2170cce3804615d5cddb8230d6a33667c741246' 
  AND token = '5RDsIZww4g9SUwCybbTC9TmUehdY5cfDzjzwu/uQSDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}