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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7591c071f6510690d60ffeb4844f277db5dfa82bd24bbed76e6c55db7b1959' 
  AND token = 'VqLw3aEn9ZoH3qR2zw0LDqqa6ehUx5XYWRIC/E14+gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}