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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5818a48171879c8e1b9edf1fbc881947884aed7ec5110ef4ad538e7155769f6b' 
  AND token = 'y4oW1prrV4cXZSO9H3M3ANTX36bw/W2O3jSb5Q5yJ/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}