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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9950b0c1b557bfd27da4287a010748927c5862884fb6d0c470b5474d233755' 
  AND token = 'nmjKSkKabGKap3HImZrMFnPwO357Jxkc0H9IG4z1oOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}