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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd94e37ccd8b76631f81444564970614f09063c5329b9f96b6d2ab07b46d4f29d' 
  AND token = 'uECmC6DRra6j42WZU+Bw5so+2+Ur33eDsyKSi3PqKIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}