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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d9452888bd57b3c0f3e587d668694eb109df67a508743621cc1f3e0f33de09' 
  AND token = 'kcQJMBVkzf9FSw3UiKnashKVTKaOsQS9eZV+LBeHbE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}