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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce36ee9d129b1a4ca70fde77513d412f81ebdf62aafc53e6d63053b3c4a2485' 
  AND token = 'ysxcCINzTDLw/HEp/o1ZgO72w+/7iPpb+lOQd4MmNBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}