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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709121282f87b879375eb963e0322b6716a2902d3960ad51cc605e317ade0471' 
  AND token = 'zFfJt6kXovAqPGVbN9Ce0wZDPKB9sv6hN2Y6RfVkx6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}