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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c760f8219b025f9189ffa85e72d8d00e68ea46c63f984c897b2bf92afb76491' 
  AND token = 'YKY5f3BKKfGY9bXqRRjsPmcu+bcgKgrEtuQ0BN77ak0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}