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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f220a621f716a67d8fe260fab77044ad18a6543f201291c00177e839d18287a' 
  AND token = '76njmW+KmGbvYnYkrrQu6SAVG/dbxwHHKWZ6TO5+TIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}