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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a050bc909b3726532f7aa0a3f281ac432cded790ec0918c75070b194fdc88e2' 
  AND token = 'IDx2E8cKMEYsT7nl/ktYu1JW0c1/SBzHs4RK9V9w3iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}