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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d3f10641e3ab6e16b0017fb3fcc1d47d8d6cd9de29c9d598dc58ef4a279c64' 
  AND token = '6I5PL45Ff7ohaOYGxMxyXGzvDz+sUG3xtpBTAFd/sTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}