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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8019c28e0f5381b429d90cb56fa45875de434756d293fbb73ade7c30008a46b' 
  AND token = '+LJ159Yq6z2kw8Cm7oJ5tWDQAKdBEVnkwJDyFA1Lz9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}