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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b1a2cd84db86821dbf44460349c86bb040ebb7795209099f1d77093020cf97' 
  AND token = 'SWkN8VRoD2FWy+AsqK0xtgOyRf6dyPsLFIvvFBm4E7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}