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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2450856ef7c2a95dc2300b790c96060e3045eecd13615e3b52de2e62d50d6687' 
  AND token = '2EhVQ6LwlZLUTV+d2U6ByAz1bMetHKeXPEV/gcATjf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}