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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd7eb1206fb061a9aa516e8dcacab7eb360e24eb5f50aff50d97a96b653a4fb' 
  AND token = 'oQFq7OfcRksnvvEaUf4VKTbA/lm9bFJkteRh1CLGJnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}