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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca694ed719eb082ba636a3169963bcd34c2899b372b1f42687043bd300e09f6b' 
  AND token = 'qnyFceRa5n2oH0pPm2M5M2TvS4COPyVSQo1vi5vR4dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}