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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e16394a1dec781a435178c09c8c2c942ea924139b0088dbc2fc0c57071b65ba' 
  AND token = 'OSzJEk91keU7bJc+DiXonPSGKLh+p+ar9URrMr8Stqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}