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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3d460ef181cca807305f65f1bed2e1b3364b6a2bfe6e960e41172da8cdf0d6' 
  AND token = '1oxR/P5GlZAoRGyB/KP+24zu1VCf/Sejfqtc2jcodZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}