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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8e758d35b235063bb3bc8b709644775f7c07a00e83959b443435206ab553a2' 
  AND token = '+NmPRKCWkFY06KPP5QKI0/0I0Z4eKbIcAbUk/xOldHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}