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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d85645cfcb016f37f2a1634afa2f9d6d03a21cef179aa0620a3bdc411070f60' 
  AND token = 'BiZTu/rfLTD7Hy7lw+IC9ATP65sGSvc52nXVjt066rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}