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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447d1d63e204bfb1cd8fc07cf65abf79fd7731b0a8e71647d46ec4dc017372c0' 
  AND token = 'PLwelJ5KqYgZl7Drz5G3Na4PjaS+7FDbFV3r9nNKnqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}