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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad21aa00d1fe346e37d33cdb522940a15dbe265d5280c5f5ce925f21b724fd0f' 
  AND token = 'pjEvgrFnDk5gqhWSpMISR75xxlNPSgvk5A6ryAyFhKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}