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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee8d351521ff6be4e67d25939516da30fc11e6f9e5832796536ed550e8ec18a' 
  AND token = 'vNuma3oj6TL8c8PE0XtSplROVtTIkERAyFocKrMRi0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}