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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2891081a2ce93a646e532f02ad07b4a4b7094fe2e34bc3026620d655c7278719' 
  AND token = 'FFhexMfz7h4LyzcYHDlVYcBkslw4IpE9dCRfkqfPUow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}