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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5f0baf0e6d3611ca550709b1366aac0431f05d0dc581894c905e974e6d1c99' 
  AND token = '/xXMmvTYdoq2knCf6dL2sSEoZKb423H5QArYGOxxyCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}